Die Klinik
Liebe Patientin, lieber Patient, liebe Angehörige,
das Team der Klinik II für Nephrologie, Rheumatologie, Diabetologie, und Allgemeine Innere Medizin begrüßt Sie herzlich auf dieser Website. Wir versuchen, Ihnen hier alles Wissenswerte über unsere Klinik zusammenzustellen.
Wir bieten Ihnen ein umfangreiches Angebot an Diagnose- und Therapieverfahren auf dem neuesten Stand von Forschung und Technik. Dabei ist uns die Abstimmung auf jeden einzelnen Patienten sehr wichtig. Falls Fragen offen bleiben, sprechen Sie uns bitte an.
Ihr Prof. Dr. Thomas Benzing
Direktor der Klinik
Research Career | |
Since 2017 | Deputy Chair of the Excellence Cluster CECAD |
Since 2015 | Vice Dean for Finances, Faculty of Medicine |
Since 2011 | Coordinator of Systems Biology of Ageing Cologne (Sybacol), UoC |
Since 2010 | Acting Director of the Center for Molecular Medicine Cologne, UoC |
Since 2007 | Co-Coordinator of the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), UoC |
Since 2007 | Full Professor of Medicine (W3), Chairman Department II of Internal Medicine, University of Cologne (UoC) |
2006–2007 | Full Professor (W3), University Hospital Freiburg, Vice-Chief Renal Division, University Hospital Freiburg |
2005–2007 | Board Member Center for Systems Biology, University of Freiburg |
2003–2005 | Heisenberg Fellow of the German Research Foundation (Associate Professor) |
2003 | Attending Physician, Department of Medicine, University of Freiburg |
2002 | Venia Legendi for Internal Medicine, Instructor in Medicine (Assistant Professor in Medicine) |
2000–2002 | Research Group Leader, University Hospital Freiburg |
1998–2000 | Research Fellow in Nephrology, BIDMC/Harvard Medical School, Boston, Fellow of the German Research Foundation (Laboratory of Gerd Walz) |
1996–1998 | Postdoctoral Fellow, Institute for Cardiovascular Physiology, University Hospital Frankfurt |
1995–1996 | Internship and Residency in Medicine, University Hospital Freiburg |
1994 | MD thesis with distinction, Thesis title: Regulation of endothelial autacoid synthesis, Department of Physiology, University of Freiburg (Laboratory of Rudi Busse) |
Medical Licensure and Board Certification | |
2014 | Human genetic counseling, Germany |
2005 | Hypertension Specialist, Deutsche Hochdruckliga |
2003 | Board Certification in Nephrology, Germany |
2002 | Board Certification in Internal Medicine, Germany |
1995 | German Medical License |
Awards and Honors (selection) | |
2018 | Elected Mentor Academicus Scholarium Internationalum of the Association of International Medical Students |
2018 | Elected Member of the American Clinical and Climatological Association (ACCA) |
2015 | Elected Member American Society of Clinical Investigation |
2015 | Congress President of the Annual Meeting of the German Society of Nephrology |
2014 | Congress President of the 10th International Podocyte Meeting |
2013 | Congress President of 29th Klenk Symposium for Molecular Medicine on Systems Approaches in Translational Medicine |
Since 2010 | Scientific Committee of the International Podocyte Meetings |
2010 | Elected Member German Academy of Sciences Leopoldina |
Since 2010 | President, Scientific Advisory Board of the KfH Foundation on Prevention of Renal Disease |
2008 | Ernst Jung-Award for Medicine, Ernst-Jung Society Hamburg |
2008 | Honorary Member of the Ludwig Heilmeyer Society |
2006 | Young Investigator Award of the American Society of Nephrology |
2005 | Advisory activity for the NIDDK and NIH, USA |
2005 | Franz-Volhard-Award, German Society of Nephrology |
2005 | Honorary Fellow of the American Society of Nephrology (FASN) |
2004 | Adalbert Buding Research Award, German Society of Hypertension |
2003 | Heisenberg Fellowship of the German Research Foundation (DFG) |
1985 | Laufenburg Award as top graduating student of the state |
Professional Societies, Memberships |
American Society of Nephrology |
German Society of Nephrology |
European Society of Nephrology ERA/EDTA |
International Society of Nephrology |
Deutsche Hochdruckliga |
Deutsche Gesellschaft für Innere Medizin |
Scientific Journals and Editorial Boards |
Editorial board member Journal of the American Society of Nephrology, Kidney International, Nephrology Dialysis Transplantation, American Journal of Physiology Cell Physiology, Science Signaling, Nature Reviews in Nephrology |
Reviewer for Cell, Science, Nature, New England Journal of Medicine, Journal of Biological Chemistry, Journal of the American Society of Nephrology, Kidney International, Nephrology Dialysis Transplantation, American Journal of Physiology, Science Signaling, Nature Reviews in Nephrology, Journal for Clinical Investigation |
Selected Publications |
Huber, T.B., B. Schermer, R.U. Muller, M. Hohne, M. Bartram, A. Calixto, H. Hagmann, C. Reinhardt, F. Koos, K. Kunzelmann, E. Shirokova, D. Krautwurst, C. Harteneck, M. Simons, H. Pavenstadt, D. Kerjaschki, C. Thiele, G. Walz, M. Chalfie, and T. Benzing (2006) Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A, 103(46): 17079-86. |
Schermer, B., C. Ghenoiu, M. Bartram, R.U. Muller, F. Kotsis, M. Hohne, W. Kuhn, M. Rapka, R. Nitschke, H. Zentgraf, M. Fliegauf, H. Omran, G. Walz, and T. Benzing (2006) The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth. J Cell Biol, 175(4): 547-54. |
Hildebrandt, F., T. Benzing, and N. Katsanis (2011) Ciliopathies. N Engl J Med, 364(16): 1533-43. |
Thadhani, R., T. Kisner, H. Hagmann, V. Bossung, S. Noack, W. Schaarschmidt, A. Jank, A. Kribs, O.A. Cornely, C. Kreyssig, L. Hemphill, A.C. Rigby, S. Khedkar, T.H. Lindner, P. Mallmann, H. Stepan, S.A. Karumanchi, and T. Benzing (2011) Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia. Circulation, 124(8): 940-50. |
Hackl, M.J., J.L. Burford, K. Villanueva, L. Lam, K. Susztak, B. Schermer, T. Benzing, and J. Peti-Peterdi (2013) Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med, 19(12): 1661-6. |
Hohne, M., C. Ising, H. Hagmann, L.A. Volker, S. Brahler, B. Schermer, P.T. Brinkkoetter, and T. Benzing (2013) Light microscopic visualization of podocyte ultrastructure demonstrates oscillating glomerular contractions. Am J Pathol, 182(2): 332-8. |
Kurschat, C.E., R.U. Muller, M. Franke, D. Maintz, B. Schermer, and T. Benzing (2014) An approach to cystic kidney diseases: the clinician's view. Nat Rev Nephrol, 10(12): 687-99. |
Benzing, T. (2015) Polycystic kidney disease. HALTing PKD progression--revival of blood pressure control. Nat Rev Nephrol, 11(3): 129-31. |
Thadhani, R., H. Hagmann, W. Schaarschmidt, B. Roth, T. Cingoez, S.A. Karumanchi, J. Wenger, K.J. Lucchesi, H. Tamez, T. Lindner, A. Fridman, U. Thome, A. Kribs, M. Danner, S. Hamacher, P. Mallmann, H. Stepan, and T. Benzing (2016) Removal of Soluble Fms-Like Tyrosine Kinase-1 by Dextran Sulfate Apheresis in Preeclampsia. J Am Soc Nephrol, 27(3): 903-13. |
Rinschen, M.M., A.K. Hoppe, F. Grahammer, M. Kann, L.A. Volker, E.M. Schurek, J. Binz, M. Hohne, F. Demir, M. Malisic, T.B. Huber, C. Kurschat, J.N. Kizhakkedathu, B. Schermer, P.F. Huesgen, and T. Benzing (2017) N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton. J Am Soc Nephrol, 28(10): 2867-2878. |
Welcker, D., M. Jain, S. Khurshid, M. Jokic, M. Hohne, A. Schmitt, P. Frommolt, C.M. Niessen, J. Spiro, T. Persigehl, M. Wittersheim, R. Buttner, M. Fanciulli, B. Schermer, H.C. Reinhardt, T. Benzing, and K. Hopker (2018) AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene, 37(11): 1503-1518. |